Prospects for genomic surveillance for selection in schistosome parasites

Schistosomiasis is a neglected tropical disease caused by multiple parasitic Schistosoma species, and which impacts over 200 million people globally, mainly in low- middle-income countries. Genomic surveillance to detect evidence for natural selection schistosome populations represents an emerging promising approach identify interpret responses ongoing control efforts or other environmental factors. Here we review how genomic variation used selection, these approaches have been applied schistosomes, future studies may be improved. We discuss the theory of analyses experimental designs such analyses, that schistosomes. then consider biological characteristics schistosomes are expected respond particularly those impacted programs. Examples include drug resistance, host specificity, life history traits, our current understanding specific genes underlie them also inherent features reproduction demography pose substantial challenges effective identification traits their bases. conclude discussing should designed improve biology, parasite changes response selection.